Busch began his coaching career at the age of 16 in his hometown of Edgewood, Kentucky. He took his first full-time position as head coach of the Northern Kentucky Piranhas age group and senior programs from 1974-78. Busch was an assistant coach for the Cincinnati Marlins from 1979-80, where he instructed current Arizona assistant coach Greg Rhodenbaugh. The Marlins placed six swimmers on the 1980 Olympic team and broke three world records.
Busch was the Swimming Head Coach for Arizona Wildcats at the University of Arizona for 22 years (1989-2011). As head coach of the Wildcats, Frank Busch transformed University of Arizona swimming and diving into one of the nation’s most powerful programs. His swimmers won 49 NCAA individual titles, 31 NCAA relay titles, and 2 NCAA team championships. While at Arizona, he also led Tucson Ford Aquatics (previously Hillenbrand Aquatics) to several national team championships.
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